BIOPHYSICS: Unraveling Another Sleeve

Unraveling Genome Biophysics.

While digitizing the human genome has been one of the major recent scientific achievements, unraveling genome structure and, more importantly, structure/function relationships has been a major preoccupation for many scientific teams worldwide. Indeed, the understanding of structure from the DNA level to nucleosomes, chromatin fibers, genes, and chromosomes holds the key to interpreting many of ...

Biophysics.

Computational Biophysics

Introduction/Group Overview The RLE Computational Biophysics Group is focused on understanding conformational changes in biomolecules that play an important role in common human diseases. The group uses an interdisciplinary approach combining computational modeling with biochemical experiments to make connections between conformational changes in macromolecules and disease progression. By emplo...

Radiation Biophysics

As valuable as the formal presentations are the informal and thoughtprovoking discussions which are well reported in the published proceedings. The booklet will be rewarding reading for those interested in the mode of action of neuromuscular blocking agents. In addition, the consideration given to drug receptor interaction, although naturally applied to the curare receptor, should prove very us...

Biophysics Letter

Many cell movements appear to be driven by the polymerization of actin. Here we show how the force of polymerization can be generated by the thermal motions of the actin filaments near the sites of polymerization. We apply the model to explain the observations that the lamel-lipodial cytoskeleton is organized into an orthogonal network interspersed with filopodial protrusions, and that the prot...